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目的 :观察氟马西尼治疗苯二氮艹卓 类 (BZs)药物中毒昏迷患者的疗效。方法 :分析比较了 13例采用氟马西尼治疗的BZs药物中毒昏迷患者与 14例与之病情相同而采用一般对症治疗患者的疗效及合并症。结果 :氟马西尼治疗组比一般对症治疗组可明显缩短BZs中毒患者入院后昏迷持续时间和住院日 (P <0 .0 1) ,也减少了导尿、血液透析、机械通气等有创治疗的使用率以及吸入性肺炎的发生率 ,无明显药物不良反应。结论 :氟马西尼治疗苯二氮 艹卓 类药物中毒昏迷患者有显著疗效。
Objective: To observe the efficacy of flumazenil in the treatment of patients with comazole class (BZs) poisoning coma. Methods: The efficacy and complications of 13 patients treated with flumazenil in the treatment of BZs poisoning and coma were compared and analyzed in 14 patients with the same condition but with general symptomatic treatment. Results: Flumazenil treatment group than the general symptomatic treatment group can significantly shorten the BZs poisoning patients coma duration and hospital stay after admission (P <0 01), but also reduce the catheterization, hemodialysis, mechanical ventilation and other invasive The use of treatment and the incidence of aspiration pneumonia, no obvious adverse drug reactions. Conclusion: Flumazenil is effective in treating patients with comazepam poisoning coma.