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为探讨血管紧张素转换酶(ACE)基因与高血压性脑卒中的关系,应用扩增片段长度多态性分析技术对101例原发性高血压患者(为上海市某街道原发性高血压确诊患者)与64例健康体检者(为同一社区接受健康体检者);80例高血压性脑卒中患者(为1997年4月至10月间上海医科大学华山医院神经内科住院或门急诊病人中确诊为脑梗塞或脑出血患者,均有高血压史)进行ACE基因插入/缺失(I/D)多态性检测.各组之间无年龄、性别差异.结果,(1)
In order to investigate the relationship between angiotensin converting enzyme (ACE) gene and hypertensive stroke, 101 patients with essential hypertension (Shanghai Essential Hypertension 80 cases of hypertensive stroke patients (April 1997 to October, Huashan Hospital, Shanghai Medical University, Department of Neurology, hospitalized or outpatient and emergency patients ACE gene insertion / deletion (I / D) polymorphism was detected in all patients who were diagnosed as cerebral infarction or cerebral hemorrhage.However, there was no difference in age and gender between the groups.Results (1)