1 Guillain-Barre综合征的历史本病属于一种免疫病,呈急性病程,常为暴发性呈多神经根神经病的炎性脱髓鞘。虽然免疫疾病机理已明确,但关于抗原问题尚不清楚。 1982年Osler首次命名为Guillain-Barre Syndrome(GBS),1916年Guillain,Barre与Strol作了详细报道,他们解释为一种神经根神经炎症候群,伴有脑脊液中白蛋白增加而不具有细胞反应;有运动障碍、深反射消失、皮肤反射存在、无客观感觉障碍、大肌群有深部压痛、神经与肌电变化不明确。Bardford,Bashford及Wilson于1918年报道此种病30例,命名为“急性感染性多神经炎(Acute infective polyneuroitis),在他们文章 1 Guillain-Barre syndrome history The disease is an immune disease, the acute course of the disease is often fulminant polyneuropathy neuritic demyelination. Although the mechanism of immune diseases has been clear, but the antigen is not clear. Osler was first named Guillain-Barre Syndrome (GBS) in 1982 and Guillain, Barre and Strol were reported in detail in 1916, and they were interpreted as a neurovascular syndrome with an increase of albumin in cerebrospinal fluid without cell response. Have dyskinesia, deep reflex disappears, there is skin reflex, objective obstruction, deep muscle tenderness, nerve and EMG change is not clear. Bardford, Bashford and Wilson reported in 1918 30 cases of this disease, named "Acute infective polyneuritis, in their article