Synthesis, Structure and Biological Activities of Novel Triazole Compounds Containing N,N-Dialkyldit

来源 :Chinese Journal of Chemistry | 被引量 : 0次 | 上传用户:zhongxuanshiye
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The two compounds, 2,2-dimethyl-4-S-(N,N-dimethyldithiocarbamato)-5-(1,2,4-triazol-1-yl)-propione (1) and 2,2-dimethyl-4-S-(N,N-diethyldithiocarbamato)-5-(1,2,4-triazol-1-yl)-3-propione (2), were prepared by reacting N,N-dialkyldithiocarbamate sodium with 2,2-dimethyl-4-bromo-5-(1,2,4-triazol-1-yl)-propione. Their structures were identified by elemental analysis, IR and 1H NMR spectroscopy. The structure of 1 has been determined by X-ray single crystal structure analysis. It crystallizes in monoclinic system with space group P21/c, a=1.2315(3) nm, b=1.2057(2) nm, c=1.2532(3) nm, =118.55(3), Z=4, V=1.6345(6) nm3, Dc=1.221 g/cm3, =0.324 mm-1 , F(000)=640, final R1=0.0449. There is obvious potentially weak CH…N intermolecular interaction in the crystal, which stabilizes the crystal structure. The result of the biological test showed that the two compounds have fungistasis and plant growth regulating activities. The two compounds 2,2-dimethyl-4-S- (N, N-dimethyldithiocarbamato) -5- (1,2,4-triazol- 1 -yl) -propione -S- (N, N-diethyldithiocarbamato) -5- (1,2,4-triazol-1 -yl) -3-propione (2), were prepared by reacting N, N-dialkyldithiocarbamate sodium with 2,2-dimethyl Their structures were identified by elemental analysis, IR and 1H NMR spectroscopy. The structure of 1 has been determined by X-ray single crystal (1, 4-triazol-1-yl) Structure analysis. It crystallizes in monoclinic system with space group P21 / c, a = 1.2315 (3) nm, b = 1.2057 (2) nm, c = 1.2532 (3) nm, = 118.55 = 1.6345 (6) nm3, Dc = 1.221 g / cm3, = 0.324 mm-1, F (000) = 640, final R1 = 0.0449. There is potentially potentially weak CH ... N intermolecular interaction in the crystal, which stabilizes the crystal structure. The result of the biological test showed that the two compounds have fungistasis and plant growth regulating activities.
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