【摘 要】
：
Objective:To explore the protective effect of remifentanil on mitochondria in rat hepatocytes subjected to ischemia-reperfusion injury and their possible mechan
【机 构】
：
Department of Anesthesiology
【出 处】
：
中国人民解放军军医大学学报（英文版）
论文部分内容阅读
Objective:To explore the protective effect of remifentanil on mitochondria in rat hepatocytes subjected to ischemia-reperfusion injury and their possible mechanism. Methods:The model of rat hepatic ischemia-reperfusion injury was used and the effect of remifentanil on the ultrastructure of mitochondria,calcium homeostasis, MDA level in mitochondria were observed. Results: In contrast with the control group, mitochondrial matrix calcium concentration, calcium concentration after calcium uptake, and the quantity of calcium uptake in low and high remifentanil concentration groups and 5-HD group are lower (P＜0. 01), and there is no difference in RHD (5-HD+remifentanil) group. The difference in MDA level between groups is insignificant. Conclusion:Remifentanil at clinical concentrations exerts a protective effect on mitochondria in rat hepatocytes subjected to ischemia-reperfusion injury, in which activating the KATP channel may be involved.
其他文献
在当前的社会发展中,水资源起着非常重要的作用.在当前的社会建设当中,人们也逐渐的认识到水资源节约和环保的意识,人们对于自身所处的环境也逐渐重视起来.随着现代化建设的
电力系统主要可以分为发电、输电、变电、配电、用电几个环节.配电网是电网的末端,直接与用户相连,也是辐射面积最广的网络.配电线路是电网向用户提供电能的最终路径,其运行
一直以来,水利在人类生产生活过程中都扮演着一个重要的角色,对我国的良好发展更是起到了积极的促进作用,而水利工程施工的各个环节阶段都与水有着直接的关系,同时也与当地的
The fibrous epulis, a common tumor-like lesion of the gingiva, appears in the interdental papilla as a result of local irritation. Lesions are asymptomatic and
目的探讨临床护理人员的身心健康问题以及如何解决这些问题。方法通过对临床护理人员身心状况的了解以及作者自身的体会以及相关文献的报导。结果(1)临床护理人员大多数存在
Spindle cell lipoma(SCL) is a benign lipomatous neoplasm typically located in the posterior neck and back of older males. It presents as a well-circumscribed ma
The mucosal immune system defends against a vast array of pathogens, yet it exhibits limited responses to commensal microorganisms under healthy conditions. The
目的探讨背阔肌肌皮瓣修复小儿胸部巨大血管瘤切除后缺损的疗效。方法用带蒂背阔肌肌皮瓣修复小儿胸部巨大血管瘤切除后缺损12例。皮瓣切取面积为18～40cm2。结果12例皮瓣全部
目的 探讨宫颈妊娠的诊治方法.方法 对9例宫颈妊娠患者的临床资料进行回顾性研究.结果 9例宫颈妊娠中,术前B超明确诊断3例,误诊6例,误诊率66.7%.1例入院后直接行全子宫切除术
目的:探讨肺癌术后并发乳糜胸的发生率、病因、临床表现、诊断及治疗.方法:回顾性分析5例肺癌术后并发乳糜胸患者的临床资料.结果:2例患者行保守治疗,3例患者沿原切口开胸行