论文部分内容阅读
作者指出,在应用0.%二甲基苯并蒽(DMBA)液涂抹仓鼠颊囊,制作口腔癌标准模型时,发现维生素E只能抑制癌变过程。目前尚未见对完全防止仓鼠颊囊癌变试验的报道。作者用致癌力较弱的0.1%DMBA矿物油溶液,对两组仓鼠(每组♀,♂各10只)的,左侧颊囊进行涂抹。每周3次,共涂抹28周(涂抹量约为0.12 mg DMBA)后处死。其中一组在涂抹同时给予维生素E,每周2次,每次10 mg。结果发现,在接受维生素E的仓鼠中,未见癌发生。而在未给予维生素E的仓
The authors point out that in the application of 0.% dimethylbenz (a) anthracene (DMBA) liquid hamster cheek pouch, the standard model of oral cancer, and found that vitamin E can only inhibit the cancerous process. There are no reports of tests to completely prevent hamster cheek pouch cancer. The authors applied the left cheek pouch to two groups of hamsters (10 in each group, ♂, ♂) with a slightly carcinogenic 0.1% DMBA mineral oil solution. Three times a week, a total of 28 weeks (smear volume is about 0.12 mg DMBA) and then sacrificed. One group was given vitamin E at the same time, twice a week for 10 mg each time. As a result, no cancer was observed in the vitamin E-receiving hamsters. In the absence of vitamin E’s warehouse