【摘 要】
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The precise and real-time sensing of the temperature within the physiological range is of great significance in biology and medicine. Here, a Zn-based metal-organic framework (MOF) named Zn-TCOMA is synthesized with good SHG performance due to its unique
【机 构】
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State Key Laboratory of Silicon Materials, Cyrus Tang Center for Sensor Materials and Applications,
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The precise and real-time sensing of the temperature within the physiological range is of great significance in biology and medicine. Here, a Zn-based metal-organic framework (MOF) named Zn-TCOMA is synthesized with good SHG performance due to its unique structure of the ligand and 3D frameworks. By encapsulating the two-photon fluorescent dye DMASE into the pores of Zn-TCOMA, the composite Zn-TCOMA?DMASE is obtained and simultaneously exhibits SHG response and two-photon fluorescence. Utilizing the intensity ratio between two-photon fluorescence of DMASE and SHG signal of Zn-TCOMA, Zn-TCOMA?DMASE exhibits ratiometric temperature sensing property at physiological temperature region of 20～60 C with high sensitivity. This MOF thermometer also shows excellent repeatability, good biocompatibility, and high temperature resolution of 0.018 C, opening a new avenue to develop diverse optical thermometric or thermographic applications in biotechnology or other areas. ?2020 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences.
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