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1例42岁女性患者,因右侧乳腺癌根治术后给予他莫昔芬10mg,1次/d长期维持治疗。后因高血压病加用厄贝沙坦150mg,1次/d。1个月后患者出现左侧颈部、腋下淋巴结及左侧乳房疼痛,经检查排除乳腺癌转移。考虑上述症状与厄贝沙坦有关,立即停用厄贝沙坦,继续使用他莫昔芬,1周后症状消失。之后,用氨氯地平和美托洛尔控制血压,上述症状未再发生。
A 42-year-old female patient received tamoxifen 10 mg once per day for long-term maintenance therapy after radical mastectomy of the right breast. After due to hypertension with irbesartan 150mg, 1 / d. One month later, the patient developed pain in the left neck, armpit lymph nodes and left breast, which was examined to rule out breast cancer metastasis. Consider the above symptoms associated with irbesartan, irbesartan immediately disabled, continue to use tamoxifen, symptoms disappeared after 1 week. After that, with amlodipine and metoprolol to control blood pressure, the above symptoms did not recur.