论文部分内容阅读
目的系统评价术前常规检查与选择性检查对白内障手术的安全性。方法按Cochrane系统评价方法,计算机检索MEDLINE(1966～2008.10)、EMbase(1980～2008.10)、Cochrane协作网眼和视力组数据库(2008年3期)、中国生物医学文献数据库(1979～2008.10),手工检索相关会议文献,纳入所有比较术前常规检查与选择性检查对白内障手术安全性的随机对照试验,并采用RevMan5.0软件进行Meta分析。结果共纳入4个随机对照试验,包括20490例患者。Meta分析结果显示,白内障手术患者,术前常规检查与选择性检查在术中全身并发症发生率[RR=1.05,95%CI(0.89,1.24),P=0.59]、术后全身并发症发生率[RR=0.97,95%CI(0.80,1.18),P=0.77]、术中眼部并发症发生率[RR=0.99,95%CI(0.74,1.33),P=0.97]及术后眼部并发症发生率[RR=1.11,95%CI(0.76,1.60),P=0.59]4方面,其差异均无统计学意义。结论术前常规检查与选择性检查相比,白内障手术患者术中、术后全身并发症发生率,以及术中、术后眼部并发症发生率差异均无统计学意义,但此结论对于危重病人的适用性有待于进一步研究。因本系统评价纳入研究较少,上述结论有待更多设计严谨的大样本随机对照试验加以验证。
Objective To systematically evaluate the safety of preoperative routine examination and selective examination on cataract surgery. Methods According to the method of Cochrane systematic review, MEDLINE (1966 ~ 2008.10), EMbase (1980 ~ 2008.10), Cochrane Collaboration Eye and Vision Group Database (3 of 2008), China Biomedical Literature Database (1979 ~ 2008.10) The relevant conference literature included all randomized controlled trials comparing routine and preoperative selective cataract surgery safety with cataract surgery and Meta-analysis using RevMan 5.0 software. Results A total of 4 randomized controlled trials were included, including 20490 patients. Meta-analysis showed that the incidence of systemic complications in preoperative cataract surgery, preoperative routine examination and selective examination [RR = 1.05,95% CI (0.89,1.24), P = 0.59] and postoperative systemic complications (RR = 0.97,95% CI 0.80,1.18, P = 0.77). The incidence of intraoperative ocular complications [RR = 0.99,95% CI (0.74,1.33), P = 0.97] There was no significant difference in the complication rate between two groups (RR = 1.11, 95% CI (0.76, 1.60), P = 0.59] 4. Conclusion Compared with selective examination, the preoperative routine examination and postoperative cataract surgery patients intraoperative and postoperative systemic complications, as well as intraoperative and postoperative complications of ocular complications were no significant difference, but this conclusion for the critical The applicability of the patient needs further study. Due to the small number of studies included in this systematic review, these conclusions need to be verified by more carefully designed large randomized controlled trials.