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患者男,82岁。右侧胸部和背部出现红斑、丘疹伴局部水肿和发硬8个月。皮肤科情况:右侧胸部和背部及右上肢皮肤水肿和发硬,胸部见大片红斑,且红斑上有红色丘疹和结节,部分皮损表面破损,有少许结痂,但无明显渗液,右侧腋窝可触及数个肿大淋巴结。右侧胸部皮损组织病理示:成团状的肿瘤细胞侵犯真皮和表皮层,累及皮肤附属器,免疫组化检查示ER(3+)、CK(3+)、HMB45(-)、S-100(-),为来源于乳腺的浸润性导管癌。诊断:乳腺浸润性导管癌;皮肤转移。并进行相关文献复习。
Male patient, 82 years old. The right side of the chest and back erythema, papules with local edema and stiff hair for 8 months. Dermatology: the right chest and back and right upper extremity skin edema and stiff hair, chest see large erythema, erythema and red papules and nodules, some of the lesion surface damage, a little crusting, but no obvious exudate, The right axillary palpable several lymph nodes. Histopathological examination of right thoracic lesions showed that agglutinative tumor cells infiltrated the dermis and epidermis, involving the skin appendages. Immunohistochemical examination showed that ER (3 +), CK (3 +), HMB45 (-), S- 100 (-), invasive breast duct cancer. Diagnosis: invasive ductal breast cancer; skin metastasis. And review the relevant literature.