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目的观察甲氨蝶呤单次肌肉注射治疗异位妊娠疗效及安全性,并探讨其应用适应症和监测指标。方法单次肌内注射甲氨蝶呤50mg/m2。注药后记录患者自觉症状和一般情况,定时进行血β-HCG水平监测和B超检查直至正常。结果61例成功,成功率达85.91%。结论严密观察下本法可适用某些过去认为不宜MTX治疗的异位妊娠者,血β-HCG水平及动态变化可作为重复注射和剖腹探查的指标,包块大小仅供参考、处理腹痛患者要慎重。
Objective To observe the efficacy and safety of a single intramuscular injection of methotrexate in the treatment of ectopic pregnancy and to explore its indications and monitoring indicators. Methods A single intramuscular injection of methotrexate 50mg / m2. After injection of patients with symptoms and the general record of patients with regular blood β-HCG level monitoring and B-ultrasound until normal. Results 61 cases were successful, the success rate of 85.91%. Conclusions Under the close observation, this method can be applied to some ectopic pregnancy in the past that it is not suitable for MTX treatment. The blood β-HCG levels and dynamic changes can be used as indexes of repeated injection and laparotomy. The size of the mass is only for reference. careful.