目的:探讨溃疡性结肠炎(Ulcerrative colitis,UC)的临床特点。方法:回顾性分析我院3年来确诊的UC住院病人54例。结果:54例患者内镜下表现为12例黏膜呈多发性浅溃疡,29例黏膜呈弥漫性充血水肿、颗粒状,13例附有血性分泌物,假性息肉形成。病理观察所有患者均表现为隐窝脓肿、浅表溃疡及杯状细胞减少,固有膜内淋巴、浆细胞和单核细胞为主的弥漫性炎症细胞浸润。结论:腹痛、腹泻、黏液脓血便为UC主要表现。 Objective: To investigate the clinical features of ulcerrative colitis (UC). Methods: A retrospective analysis of our hospital in 3 years confirmed 54 cases of UC inpatients. Results: The endoscopic findings of 54 patients showed multiple mucosal ulceration in 12 cases, diffuse congestion and edema in 29 mucosa, granuliform, and 13 cases with bloody discharge and pseudo polyp formation. Pathological observation of all patients showed crypt abscess, superficial ulcers and goblet cells decreased, inherent membrane lymphatic, plasma cells and monocytes predominant diffuse inflammatory cell infiltration. Conclusion: Abdominal pain, diarrhea and mucus purulence are the main manifestations of UC.