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最近已获得若干和“活化依赖”的抗血小板单克隆抗体(单检),应用这些单抗-流式细胞计可直接检测活化血小板。本文综述近期有关这方面的研究进展及论述其在临床上应用。活化-依赖的单克隆抗体在止血时血小板浆膜的若干成分与血管壁内某些物质,其它血小板表面成分及凝固蛋白发生相互作用,其中一些相互作用需有
Recently, several anti-platelet monoclonal antibodies (single assays) have been obtained that are “activation dependent” and can be used to directly detect activated platelets using these mAbs-flow cytometers. This article summarizes the recent research progress in this area and discusses its clinical application. Activated - dependent monoclonal antibodies in hemostasis when the platelet serosonin some of the components of the blood vessel wall and some substances, other platelet surface composition and coagulation protein interaction, some of the interactions need to have