论文部分内容阅读
目的:探讨经结肠镜高位药物局部灌肠联合常规药物口服治疗溃疡性结肠炎临床疗效。方法:将158例溃疡性结肠炎患者,分为两组治疗。治疗组80例采用经结肠镜检查方法,达右半结肠病变部位以上,将药物通过喷洒管注入肠道局部治疗联合美沙拉嗪片等药物口服治疗,灌肠每周2次,14天为一个疗程,共治疗3个疗程;对照组78例用美沙拉嗪片口服及内科基础治疗。观察两组临床疗效及镜下变化情况。结果:治疗组患者总有效率为97.50%;对照组为88.46%;两组疗效比较差异有统计学意义(P<0.05)。结论:采用结肠镜高位灌肠联合美沙拉嗪综合治疗疗效好,且通过灌肠治疗可直观肠粘膜恢复情况。
Objective: To investigate the clinical efficacy of oral enema combined with conventional drugs in the treatment of ulcerative colitis through colonoscopy. Methods: 158 patients with ulcerative colitis were divided into two groups. 80 cases of treatment group by colonoscopy, up to the right half of the lesion in the colon above the drug through the sprinkler tube into the intestinal local treatment combined with Mesalazine tablets and other drugs oral treatment enema twice a week for 14 days for a course of treatment , A total of three courses of treatment; 78 cases of the control group with Mesalazine tablets oral and basic medical treatment. The clinical efficacy and microscopic changes of the two groups were observed. Results: The total effective rate was 97.50% in the treatment group and 88.46% in the control group. The difference between the two groups was statistically significant (P <0.05). Conclusion: The high-dose colon enema combined with mesalazine comprehensive treatment is effective, and through the enema can be intuitive intestinal mucosal recovery.