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CT或其他影像学方法定位诊断异位和(或)恶性嗜铬细胞瘤及其转移灶常有困难,本研究对25例经手术或病理检查诊断为异位和(或)恶性嗜铬细胞瘤及其转移灶的患者行~(131)I-间位碘代苄胍(MIBG)定位显像,部分病例与CT和B超进行了比较。结果25例~(131)I-MIBG显像的检出率为100%;CT和B超的检出率各为45.5%和81.8%。CT检出率低主要由于小而分散的肿瘤在腹腔内不易与肠腔的断面相区分所致。~(131)I-MIBG诊断异位和(或)恶性嗜铬细胞瘤及其转移灶,特别对腹腔内小而分散的肿瘤具有较高的灵敏度及特异性。
Localization of ectopic and/or malignant pheochromocytoma and its metastases by CT or other imaging methods is often difficult. In this study, 25 cases of ectopic and/or malignant pheochromocytoma were diagnosed by surgery or pathology. Patients with metastatic lesions were treated with ~(131)I-meta-o-benzylcholine (MIBG) localization imaging, and some cases were compared with CT and B ultrasound. Results The detection rate of 25 cases with 131 I-MIBG imaging was 100%. The detection rates of CT and B ultrasound were 45.5% and 81.8%, respectively. The low rate of CT detection is mainly due to the fact that small, scattered tumors are not easily differentiated from the section of the intestine in the abdominal cavity. 131I-MIBG is used to diagnose ectopic and/or malignant pheochromocytoma and its metastases, especially for the small and scattered tumors in the abdominal cavity with high sensitivity and specificity.