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目的 观察不稳定型心绞痛 (UAP)患者介入治疗前后心肌肌钙蛋白I(cTnI)的变化特点。方法 选取接受冠状动脉介入治疗的UAP患者 49例 ,按照病变特征分为三组 ,术中测定球囊扩张时间、球囊最大充盈压 (MIP) ,并于术前 ,术后 1、6、2 4、48小时检测cTnI水平。结果 A型病变组球囊扩张时间、MIP均明显小于B、C型病变组。 2 4小时后A型病变组cTnI水平明显低于B、C型病变组。结论 UAP患者介入治疗后cTnI水平升高 ,其中C型病变升高明显 ,需进一步给予改善心肌代谢的药物辅助治疗。
Objective To investigate the changes of cardiac troponin I (cTnI) in patients with unstable angina pectoris (UAP) before and after interventional therapy. Methods Forty-nine patients with UAP undergoing coronary intervention were divided into three groups according to their pathological features. The duration of balloon dilation and the maximum filling pressure (MIP) 4,48 hours to detect cTnI levels. Results The time of balloon dilatation and MIP in type A lesion group were significantly less than those in type B and C lesion group. After 24 hours, the level of cTnI in type A lesions was significantly lower than that in type B and C lesions. Conclusions The level of cTnI in UAP patients after interventional therapy is elevated, of which the type C lesions are obviously increased. Drug-assisted therapy to improve myocardial metabolism should be given further.