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作者报道10例β阻滞剂治疗中发生的牛皮癣(6例)或原有的牛皮癣明显恶化(4例)。其中4例表现典型的甲变化(凹陷及甲松离),3例有关节症状,2例有典型的掌跖牛皮癣损害。治疗中出现的牛皮癣损害,停药后4例完全愈合,另外5例愈合80%,1例于缓解后11个月复发。1例于7个月后再用阿替洛尔(共4个月),再次服药2个月后全身皮肤发生牛皮癣。作者指出,β阻滞剂可引起牛皮癣复发或加重。Arntzen等曾报道,23例牛皮癣病
The authors reported a significant worsening of psoriasis (n = 6) or psoriasis (n = 4) that occurred in 10 patients with beta-blocker therapy. Four of them showed typical changes of A (sag and psoralen), three had symptomatic symptoms, and two had typical palmar plantar psoriasis lesions. Psoriasis damage occurred in treatment, 4 cases were completely healed after stopping, the other 5 cases healed 80%, 1 case relapsed 11 months after remission. One case was treated with atenolol for 7 months (total 4 months), and psoriasis occurred on the whole body skin after 2 months of treatment. The authors point out that beta blockers can cause recurrence or aggravation of psoriasis. Arntzen et al reported that 23 cases of psoriasis disease