本文报道了1例肝癌患者服用索拉非尼片后出现高血压、呕吐、全身皮疹、瘙痒、脱发、骨髓抑制、腹泻等一系列典型不良反应,分别予培哚普利、硝苯地平控制血压,甲氧氯普胺止吐,氯雷他定、氢化可的松、甲泼尼龙抗过敏,重组人粒细胞集落刺激因子升高粒细胞,蒙脱石散止泻,不良反应得到有效控制。 This article reports a series of typical adverse reactions such as hypertension, vomiting, systemic rashes, itching, hair loss, myelosuppression and diarrhea in a patient with liver cancer after taking sorafenib tablets. The patients were treated with perindopril and nifedipine to control blood pressure , Metoclopramide antiemetic, loratadine, hydrocortisone, methylprednisolone anti-allergy, recombinant human granulocyte colony-stimulating factor increased granulocytes, montmorillonite powder diarrhea, adverse reactions are effectively controlled.