论文部分内容阅读
为了解高甘油三酯血症与糖尿病发病的关系,在432例非糖尿病人群中分析了空腹血浆甘油三酯(FTG)水平对糖尿病发病率的影响。按初检时FTG水平从低到高,以计算机分成三组,最高甘油三酯(TG)组(为2.5mmol/L,相当于221.4mg/dl),6年非胰岛素依赖型糖尿病发病率是最低TG组(为0.7mmol/L,相当于60.3mg/dl)的2.3倍(38.6%对16.6%,P<0.01),6年后口服葡萄糖耐量试验2小时血糖(OGTTBG2h)平均值高2.4mmol/以(43mg/dl,即180.3mg/dl对137.4mg/dl)。进行多因素线性回归分析,调整年龄、性别、空腹血糖(FBG)和体重指数诸影响因素后,FTG水平仍与6年后OGTTBG2h水平显著正相关(P=0.0335)。表明FTG水平升高是糖尿病发病的独立危险因素。
To understand the relationship between hypertriglyceridemia and the incidence of diabetes, we analyzed the effect of fasting plasma triglycerides (FTG) on the incidence of diabetes in 432 non-diabetic subjects. According to the initial examination, FTG levels were from low to high, divided into three groups by computer, the highest triglyceride (TG) group (2.5mmol / L, equivalent to 221.4mg / dl), 6 years of non-insulin dependent diabetes mellitus Rates were 2.3-fold (38.6% versus 16.6%, P <0.01) for the lowest TG group (0.7 mmol / L, equivalent to 60.3 mg / dl) after 6 years of oral glucose tolerance The average blood glucose level (OGTTBG2h) was 2.4 mmol / L (43 mg / dl, ie 180.3 mg / dl vs. 137.4 mg / dl) for 2 hours. After adjusting for age, sex, fasting blood glucose (FBG) and body mass index, the level of OGTTBG2h was still positively correlated with OGTTBG2h level after 6 years (P = 0.0335) by multivariate linear regression analysis. This indicates that elevated FTG levels are an independent risk factor for diabetes.