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我院于1996 年4 月1997 年12 月,对75 例中、晚期异常妊娠(因胎儿异常而终止妊娠66 例,自然流产9 例)的孕妇及其胎儿进行了TORCH检测及染色体分析。结果:TORCH 感染阳性孕妇68 例,占异常妊娠病例的90 .66% 。胎儿畸形中,神经管缺损(NTD)58 例,占异常胎儿的87.87% ,其孕妇均与HSV 感染有关。胎儿染色体异常4 例,其中3 例孕母合并HSV感染。提示:弓形体、病毒感染是导致胎儿基因突变、染色体异常和畸形、死亡的主要因素之一;孕前及孕早期检测TORCH及防治是降低围产儿死亡率,提高优生水平的重要措施之一。
Our hospital in April 1996 December 1997, 75 cases of abnormal pregnancy (due to abnormal fetal termination of pregnancy in 66 cases, 9 cases of spontaneous abortion in pregnant women and their fetuses TORCH detection and chromosome analysis. Results: 68 cases of TORCH positive pregnant women, accounting for 90 cases of abnormal pregnancy. 66%. Fetal deformity, neural tube defects (NTD) in 58 cases, accounting for 87.87% of abnormal fetuses, their pregnant women are associated with HSV infection. Fetal chromosome abnormalities in 4 cases, of which 3 pregnant women with HSV infection. Toxoplasma gondii and viral infection are one of the major causes of fetal genetic mutation, chromosomal abnormality and deformity and death. Detecting TORCH before and during the first trimester and preventing and controlling TORCH are one of the important measures to reduce perinatal mortality and improve the level of eugenics.