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目的观察喜炎平联合干扰素雾化吸入治疗手足口病的临床效果。方法 72例手足口病患儿,随机分为治疗组和对照组,各36例。治疗组应用喜炎平联合干扰素雾化吸入治疗,对照组应用利巴韦林治疗。观察两组临床症状、体征的变化时间并对其分析。结果两组总有效率比较差异有统计学意义(P<0.05);治疗组体温恢复正常时间、皮肤黏膜丘疱疹消退时间短于对照组(P<0.05)。结论喜炎平联合干扰素治疗手足口病可以缩短患儿体温恢复正常时间、皮肤黏膜丘疱疹消退时间,疗效显著。
Objective To observe the clinical effect of Xiyanping combined with interferon atomizing inhalation in treating hand-foot-mouth disease. Methods 72 cases of hand, foot and mouth disease were randomly divided into treatment group and control group, 36 cases in each. The treatment group was treated with Xiyanping combined with interferon inhalation, while the control group was treated with ribavirin. The changes of clinical symptoms and signs in the two groups were observed and analyzed. Results There was significant difference in total effective rate between the two groups (P <0.05). The body temperature returned to normal in the treatment group, and the subdural time of skin and mucocutaneous herpes was shorter than that of the control group (P <0.05). Conclusion Xiyanping combined with interferon in the treatment of hand, foot and mouth disease can shorten the normal temperature in children with recurrent skin mucociliary herpes subduction time, the effect is significant.