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目的观察氨氯地平、双克、坎地沙坦联合治疗难治性高血压的疗效。方法选择难治性高血压患者74例,随机分为治疗组和对照组各37例。治疗组服用氨氯地平、双克,除糖尿病和高尿酸血症外,加服坎地沙坦或呋塞米;对照组除双克、呋塞米与治疗组相同外,服用硝苯地平片或非洛地平、依那普利或贝那普利。结果治疗组总有效率86.5%,对照组总有效率64.9%。结论氨氯地平、双克、坎地沙坦三种药物联合治疗难治性高血压效果显著且不良反应小,值得在临床上推广应用。
Objective To observe the therapeutic effect of amlodipine, diazepam and candesartan in the treatment of refractory hypertension. Methods 74 patients with refractory hypertension were randomly divided into treatment group and control group, 37 cases each. The treatment group taking amlodipine, two grams, in addition to diabetes and hyperuricemia, plus service candesartan or furosemide; control group in addition to double grams, furosemide with the same treatment group, taking nifedipine tablets Or felodipine, enalapril or benazepril. Results The total effective rate was 86.5% in the treatment group and 64.9% in the control group. Conclusion Amlodipine, two grams, candesartan three drugs combined treatment of refractory hypertension significant effect and adverse reactions, it is worth in the clinical application.