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1984年10月在东京举行了日本鼻科学会第23届年会,就鼻息肉(NP)病原和发病学进行了讨论,阐述了什么是NP以及它是如何形成的这些令人困惑的问题。以下是讨论会记录的节译文。鼻恩肉神经的组织化学研究平出(Hiraide F)等用10个成人的NP和5块下鼻甲粘膜进行组织化学染色观察,发现标本组织中有胆碱脂酶,酶的强活性限于下鼻甲粘膜的神经纤维中。染色的神经纤维可能是副交感神经纤维。这些胆碱能纤维分布在腺体周围。浆液腺的胆碱能纤维似比粘液腺者多。鼻粘膜小血管周围也有很多胆碱能纤维。上皮细胞和结缔组织细胞中未见酶活性。NP中未见到胆碱能纤维,腺体、小动脉和动脉周围也无酶反应。下鼻甲粘膜小动脉周围可见很多肾上腺素能纤维。除了蒂部有少量神经纤维外,整个NP包括血管和腺体均无肾上腺素能纤维。讨论:本文组织化学研究发现胆碱能和肾上腺素能神经纤维存在于下鼻甲粘膜,部分见于NP蒂部,而不见于大部NP组织,说明NP腺体和血管无植物神经分布,故而支持植物神经功能失调是NP发生的主
The 23rd annual meeting of the Japanese Society of Nasal Sciences was held in Tokyo in October 1984 to discuss the pathogenesis and pathogenesis of nasal polyps (NP) and to elaborate on these puzzling questions about what is NP and how it is formed. The following is a section of the seminar record translation. Harnide F nerve histochemistry (Hiraide F) with 10 adult NP and 5 inferior turbinate mucosa histochemical staining showed that specimens of tissue with cholinesterase, strong activity of the enzyme is limited to the inferior turbinate Mucosal nerve fibers. Dyed nerve fibers may be parasympathetic fibers. These cholinergic fibers are distributed around the glands. Serous glands of cholinergic fibers than Mucous glands and more. There are many cholinergic fibers around the small nasal mucosa. No enzymatic activity was found in epithelial and connective tissue cells. NP did not see cholinergic fibers, glands, arteries and arteries around the enzyme-free reaction. A lot of adrenergic fibers are seen around the inferior turbinate mucosal artery. Except for a small amount of nerve fibers in the pedicle, the entire NP includes no adrenergic fibers in the blood vessels and glands. Discussion: The histochemical study found that cholinergic and adrenergic nerve fibers in the inferior turbinate mucosa, found in part of the NP pedicle, but not found in most of the NP tissue, NP gland and blood vessels without autonomic distribution, and thus support the plant Nerve dysfunction is the main occurrence of NP