【摘 要】
:
ObjectiveTo determine the quality of life of patients treated with one of three different types of surgery for breast cancer.MethodsThis was a cross-sectional study using a questionnaire survey comple
【机 构】
:
230022 安徽医科大学第一附属医院乳腺外科,230022 安徽医科大学第一附属医院乳腺外科,230022 安徽医科大学第一附属医院乳腺外科,230022 安徽医科大学第一附属医院乳腺外科,
论文部分内容阅读
ObjectiveTo determine the quality of life of patients treated with one of three different types of surgery for breast cancer.
MethodsThis was a cross-sectional study using a questionnaire survey completed by Chinese patients without active disease after at least 2 years of follow-up after breast cancer surgery.
ResultsThis study totally included 139 breast cancer patients: 44(31.6%)had undergone modified radical mastectomy with reconstruction, 41(29.5%)had a quadrantectomy with axillary lymph node dissection, and 54(38.9%)had a modified radical mastectomy without reconstruction. The EORTC QLQ-C30 and EORTC QLQ-BR23 questionnaires were used; their reliability was>0.82. Global health status(94.30±12.04, P=0.028)and role functioning(85.16±17.23, P=0.138)were highest in the quadrantectomy group. Pain score was highest in the modified radical mastectomy with reconstruction group(26.13±30.15, P=0.042). The breast symptom score(22.56±22.30, P=0.009)and body image perception(85.56±19.72, P=0.025)were highest in the conservative treatment group. The overall health of patients given modified radical mastectomy without reconstruction was lower(72.61±20.89, P=0.014)in women older than 50 years compared with younger women.
ConclusionsThe quadrantectomy with axillary lymph node dissection procedure had better acceptance, but the overall health status did not differ between groups. Overall health status is lower in women older than 50 years receiving a modified radical mastectomy without reconstruction.
其他文献
目的探讨甲状腺癌甲状腺全切除术后低钙血症的影响因素。方法回顾性分析中国医学科学院肿瘤医院2009年6月至2011年12月650例甲状腺癌甲状腺全切术患者临床资料,研究年龄、性别、原发灶分期、原发灶是否初治、颈淋巴清扫、气管食管沟淋巴清扫、甲状旁腺意外切除(inadvertent parathyroidectomy,IPE)和采用精细被膜解剖技术与术后持续性低钙血症关系。影响术后血钙水平单因素差异比
目的分析不同月经状况妇女的乳腺症状和超声特点与女性激素水平的关系。方法征集正常月经妇女53例、绝经过渡期129例和绝经后318例,记录乳腺症状及时间;正常月经妇女在黄体期行超声检查和血清雌二醇(E2)和孕酮(P)水平测定;其他妇女行超声检查及血清雌二醇水平测定。结果①60.4%(32/53)正常月经妇女及57.4%(74/129)过渡期妇女有乳房胀疼,乳房胀疼者血清E2、P水平相对较高;12.5%
目的对胰腺假性囊肿(pancreatic pseudocyst,PPC)的治疗方式和临床效果进行分析。方法对2002年1月至2012年6月收治的78例PPC的治疗方式、效果、并发症进行回顾性分析。结果保守治疗20例,在随访期间均能自行吸收。手术治疗58例:包括经皮穿刺置管引流术3例,术后1例出现胰瘘,1例并发脓肿;PPC外引流术5例,术后有2例出现胰瘘,1例出现出血;PPC-胃吻合15例,术后有1
目的研究乙酰肝素酶(heparanase,Hpa)、尿激酶纤溶酶原激活剂(urokinase type plasminogen activator,uPA)在甲状腺癌组织中的表达与淋巴结转移的关系。方法采用免疫组化SP法检测113例甲状腺癌及134例良性甲状腺结节组织中Hpa、uPA蛋白的表达情况,分析Hpa、uPA蛋白在甲状腺癌中表达及其临床意义。结果Hpa、uPA在甲状腺癌及良性甲状腺结节组织
目的探讨胃旁路术(gastric bypass,GBP)治疗不同体重指数(body mass index,BMI)的2型糖尿病(type 2 diabetes mellitus,T2DM)的临床效果。方法将宝鸡人民医院2012年9月至2013年7月间行手术治疗的T2DM分为2组:肥胖组BMI≥28 kg/m2)16例,超重组(BMI<28 kg/m2)21例,均行GBP。观察术后3、6个月患者空腹
目的探讨抑癌基因PTEN和基质金属蛋白酶9(MMP-9)及血管内皮生长因子C(VEGF-C)在大肠癌组织中的表达及相关性。方法应用免疫组化SP法检测102例大肠癌组织及30例正常大肠黏膜组织中PTEN、MMP-9和VEGF-C的表达,并分析其与大肠癌临床病理特征的关系。结果本组大肠癌与癌旁组织中PTEN阳性表达率分别为54.9%(56/102)和100%(30/30),MMP-9阳性表达率分别为8