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目的观察在常规治疗基础上加用黄葵胶囊联合阿魏酸钠治疗原发性肾病综合征的临床疗效。方法采用病例对照研究,将46例患者随机分为治疗组(23例)和对照组(23例),两组患者均给予常规治疗,治疗组在常规治疗基础上加用黄葵胶囊及阿魏酸钠口服,以28 d为1疗程,比较两组治疗前后血浆白蛋白、24 h尿蛋白定量、血肌酐、尿素氮、血脂变化及临床疗效。结果治疗后两组临床症状均减轻或消失,治疗组有效率86.96%,对照组有效率65.22%,差异有统计学意义(P<0.05),在血浆白蛋白、24 h尿蛋白定量、血肌酐、血脂等指标改善方面,治疗组明显优于对照组,差异有统计学意义(P<0.05)。结论黄葵胶囊联合阿魏酸钠治疗原发性肾病综合征具有一定效果。
Objective To observe the clinical curative effect of adding Huang Kui capsule combined with sodium ferulate on the treatment of primary nephrotic syndrome. Methods A case-control study was conducted. Forty-six patients were randomly divided into treatment group (23 cases) and control group (23 cases). Both groups were given conventional treatment. The treatment group was given Huang Kui Capsule Oral sodium to 28 d for a course of treatment before and after treatment, serum albumin, 24 h urinary protein, serum creatinine, blood urea nitrogen, blood lipid changes and clinical efficacy. Results After treatment, the clinical symptoms of both groups were reduced or disappeared. The effective rate was 86.96% in the treatment group and 65.22% in the control group, the difference was statistically significant (P <0.05). The serum albumin, 24h urinary protein, , Blood lipid and other indicators of improvement, the treatment group was significantly better than the control group, the difference was statistically significant (P <0.05). Conclusion Huang Kui capsule combined with sodium ferulate in the treatment of primary nephrotic syndrome has some effect.