近年来,我们应用鼻唇沟皮瓣一次性修复唇、舌及口底组织缺损5例,均获满意效果。现报道如下。1　临床资料11　一般资料　右侧舌癌2例,行原发灶、下颌骨部分切除加双侧功能性颈清术,缺损右侧半舌;下颌龈癌1例,行原发灶、下颌骨部分切除加双侧舌骨上清扫术,口底缺损约为45ｃｍ×25 In recent years, we apply the nasolabial fold flap to repair the lip, tongue and mouth tissue defect in 5 cases at a time, all of which have satisfactory results. Report as follows now. 1 Clinical data 11 General Information 2 cases of right tongue cancer, primary tumor, partial removal of the mandible and bilateral functional neck dissection, right flank desease tongue; gingival cancer in 1 case, the primary tumor, mandible Partial resection plus bilateral hyoid bone cleaning, mouth defect is about 45cm × 25