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目的:探讨通脉保心汤治疗舒张性心力衰竭的临床疗效。方法:将210例舒张性心力衰竭患者随机分为两组各105例。对照组予基础治疗及依那普利治疗,治疗组在对照组基础上予通脉保心汤治疗。结果:治疗组总有效率为93.3%,对照组总有效率为82.9%,治疗组优于对照组,差异有统计学意义(P<0.05)。治疗后治疗组的血浆BNP浓度、中医症状评分、生活质量评分均低于对照组,6 min步行试验优于对照组,差异均有统计学意义(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:通脉保心汤治疗舒张性心力衰竭有较好的临床疗效。
Objective: To explore Tongmai Baoxin Decoction for the treatment of diastolic heart failure. Methods: 210 patients with diastolic heart failure were randomly divided into two groups of 105 cases. The control group was given basic treatment and enalapril treatment. The treatment group was treated with Tongmai Baoxin Decoction on the basis of the control group. Results: The total effective rate was 93.3% in the treatment group and 82.9% in the control group. The treatment group was superior to the control group with statistically significant difference (P <0.05). After treatment, plasma BNP concentration, TCM symptom scores and quality of life scores of the treatment group were lower than those of the control group. The 6-minute walk test was superior to the control group (P <0.05). The incidence of adverse reactions in the two groups, the difference was not statistically significant (P> 0.05). Conclusion: Tongmai Baoxin Decoction has better clinical efficacy in treating diastolic heart failure.