【摘要】目的：觀察降阶梯方案治疗在重症获得性下呼吸道感染中的临床疗效。方法：选取2008年12月-2011年12月笔者所在医院ICU重症获得性下呼吸道感染患者32例，随机分为降阶梯治疗的观察组和传统治疗的对照组，对两组抗感染效果和控制所需时间进行对比分析。结果：观察组经过治疗后，有效率为81.25%，对照组有效率为62.50%，观察组高于对照组，比较差异有统计学意义(P<0.05)。观察组感染控制时间(7.5±2.1)d；对照组为(12.1±3.8)d，观察组短于对照组，差异有统计学意义(P<0.05)。结论：降阶梯治疗在ICU重症获得性下呼吸道感染的治疗中效果较好，且感染控制时间较短。
　　【关键词】降阶梯治疗；ICU；重症获得性下呼吸道感染
　　De-escalation Therapy of Severe Lower Airway Infection and Its Clinical Use in ICU/WU Zhi-long.//Medical Innovation of China，2012，9(16):030-031
　　【Abstract】Objective:To use de-escalation therapy for the severe lower airway infection in the ICU，and estimate the curative effect.Methods:32 patients of severe lower airway infection from 2008 to 2011，randomly divided into two groups，observation group and control group.To compare their adequate the days from the treatment beginning to the infection controlled.Results：The observation group after treatment，the effective rate was 81.25%，the effective rate of control group was 62.50%，the observation group was better than the control group，the difference was statistically significant (P<0.05).The observation group infection control time(7.5±2.1)d;control group (12.1±3.8)d，observation group was shorter than the control group，the difference was statistically significant(P<0.05).Conclusion:Using de-escalation therapy in ICU for severe lower airway infection would have better curative effect.
　　【Key words】De-escalation therapy;ICU;Severe lower airway infection
　　First-author’s address:Shihezi People’s Hospital，Shihezi 832000，China
　　doi:10.3969/j.issn.1674-4985.2012.16.015