脊索瘤起源于人体残余器官或异位性骨化组织。McMaster等[1]报道脊索瘤人群发病率为9.5%;发病年龄3~95岁,平均58.5岁,40岁以下较罕见。颅底脊索瘤约占原发颅内肿瘤的0.1%~0.2%[2]。脊索瘤起源于脊柱占62%、颅骨占32%、外轴骨骼及其他边界不清者约6%[2]。颅底脊索瘤好发于斜坡区。脊索瘤患者常以颅神经损害(其中以动眼神经和外展神经症状常见)、 Chordoma originated in the human residual organ or atopic ossification. McMaster et al [1] reported a chordoma population incidence of 9.5%; onset age 3 to 95 years, mean 58.5 years old, 40 years of age are rare. Skull base chordoma accounts for about 0.1% of intracranial tumors 0.2% [2]. Chordoma originated in the spine accounted for 62%, skull 32%, outer shaft bones and other unclear border about 6% [2]. Skull base chordoma occurs in the slopes. Chordoma patients often with cranial nerve damage (including oculomotor nerve and abducens nerve symptoms are common),