Questions: Has the goal of the declaration of St. Vincent, a comparable delivery outcome for women with and without diabetes mellitus (DM), been achieved in the region of Thuringia in Germany? Patients and Methods: In 77 women with DM type 1 and 8 women with DM type 2 we analyzed the association of glucose metabolism (Hba1c preconceptual and on pregnancy diagnosis, mean blood sugar self monitoring for each gestational month), frequency of abortions and congenital malformations. Results: Only 43.5%of the women consulted a diabetologist before conception (1-6 months). The first consultation during pregnancy was in the 9th gestational week (3-33). The prevalence of stillbirths did not differ from that of women without diabetes (DM 1.2%vs perinatal registry of the University of Jena 0.7%, n.s.). 4.7%of all pregnancies ended with an abortion. Hba1c (normal range 4.58-5.90%)was significantly higher during organogenesis (Hba1c abortion 10.5 ±3.6 vs no abortion 7.2 ±1.5%; p < 0.001). None of the women with an abortion had consulted a diabetologist before conception. The prevalence of congenital malformations ininfants of diabetic mothers was significantly higher compared with that of women without DM (17.6 vs 3.1%; p < 0.001). Mothers of those infants with congenital malformations had a significantly higher Hba1c before conception (8.7 ±1.7 vs 7.5 ±1.7%; p < 0.03), displayed significantly higher mean blood glucose (5-8 gestational week 8.0 ±1.7 vs 6.4 ±1.4 mmol/l; p < 0.01. 9-12 gestational week: 5.8 ±1.0 vs 7.1 ±1.8 mmol/l; p < 0.01) and had their first visit to a diabetologist at a later date (17 ±9 versus 10 ±6 gestational week; p < 0.001). Conclusion: The cause of frequent infant congenital malformations and abortions of mothers with DM is hyperglycemia during conception and the 1st trimenon and the lack of special care by diabetologists during these periods. Mothers of those children without congenital malformations typical for DM had a near normoglycemic glycemic control with an Hba1c < 6.3%and mean blood glucose < 6.4mmol/l. Questions: Has the goal of the declaration of St. Vincent, a comparable delivery outcome for women with and without diabetes mellitus (DM), been achieved in the region of Thuringia in Germany? Patients and Methods: In 77 women with DM type 1 and 8 women with DM type 2 we analyzed the association of glucose metabolism (Hba1c preconceptual and on pregnancy diagnosis, mean blood sugar self monitoring for each gestational month), frequency of abortions and congenital malformations. Results: Only 43.5% of the women consulted a diabetologist The first consultation during pregnancy was in the 9th gestational week (3-33). The prevalence of stillbirths did not differ from that of women without diabetes (DM 1.2% vs perinatal registry of the University of Jena 0.7%, ns). 4.7% of all pregnancies ended with an abortion. Hba1c (normal range 4.58-5.90%) was significantly higher during organogenesis (Hba1c abortion 10.5 ± 3.6 vs no abortion 7.2 ± 1.5%; p <0.001). None of the women with an abortion had consulted a diabetologist before conception. The prevalence of congenital malformations in infants of diabetic mothers was significantly higher than with that of women without DM (17.6 vs 3.1%; p <0.001). Mothers of those infants with congenital malformations had A significantly higher Hba1c before conception (8.7 ± 1.7 vs. 7.5 ± 1.7%; p <0.03) showed significantly higher mean blood glucose (5-8 gestational week 8.0 ± 1.7 vs. 6.4 ± 1.4 mmol / 12 gestational week: 5.8 ± 1.0 vs 7.1 ± 1.8 mmol / l; p <0.01) and had their first visit to a diabetologist at a later date (17 ± 9 versus 10 ± 6 gestational week; p <0.001). Conclusion: The cause of frequent infant congenital malformations and abortions of mothers with DM is hyperglycemia during conception and the 1st trimenon and the lack of special care by diabetologists during these periods. Mothers of those children without congenital malformations typical for DM had a near normoglycemic gly cemic control with an Hba1c <6.3% and mean blood glucose <6.4 mmol / l.