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目的:观察咪达唑仑镇静遗忘麻醉在结肠镜检查中应用的有效性和安全性。方法:120例自愿行咪达唑仑麻醉下结肠镜检查的患者,于检查前静注咪达唑仑镇静,检查结束以氟马西尼拮抗,观察麻醉疗效。结果:本组均对指令性语言有反应,可以与医生交谈并配合改变体位。平均动脉压、心率、血氧饱和度无统计学差异(P>0.05)。恶心、屏气、腹胀等不良反应明显减少。无一例有呼吸抑制的表现。结论:咪达唑仑用于结肠镜检查是安全的,能明显减轻患者痛苦,且方便易行。
Objective: To observe the effectiveness and safety of midazolam sedation and amnesia in colonoscopy. Methods: A total of 120 patients undergoing colonoscopy under midazolam anesthesia were sedated with midazolam sedation before the test, and were treated with flumazenil at the end of the test to observe the effect of anesthesia. Results: All patients responded to the directive language and could talk with the doctor and change the position. Mean arterial pressure, heart rate, oxygen saturation no significant difference (P> 0.05). Nausea, breath holding, bloating and other adverse reactions decreased significantly. No case of respiratory depression performance. Conclusion: Midazolam for colonoscopy is safe, can significantly reduce the pain of patients, and easy to operate.