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结直肠癌是临床较为常见的恶性肿瘤,在全世界恶性肿瘤发病率中男性占第四位,女性占第三位~([1])。其主要的治疗手段是手术,但一半以上的患者在术后复发或转移,为减轻复发或转移,新辅助或辅助化疗显得尤为重要。XELOX方案(奥沙利铂+卡培他滨)是我科常用的化疗方案之一,因不良反应低、疗效不亚于其他方案,目前临床应用广泛。奥沙利铂为第三代铂类抗癌药物,肾毒性和耳毒性明显低于顺铂~([2]);卡培他滨口服后经肠完整吸收,最
Colorectal cancer is a relatively common malignant tumor in the world, the incidence of malignant tumors in the world accounted for the fourth man, the third female (~) [1]. The main treatment is surgery, but more than half of patients relapse or metastasis after surgery, to reduce the recurrence or metastasis, neoadjuvant or adjuvant chemotherapy is particularly important. XELOX regimen (oxaliplatin + capecitabine) is one of the chemotherapy regimens commonly used in our department. Its efficacy is no less than that of other regimens because of its low adverse reactions. It is currently used in a wide range of clinical applications. Oxaliplatin is the third generation of platinum anticancer drugs, nephrotoxicity and ototoxicity was significantly lower than that of cisplatin ~ ([2]); capecitabine after oral administration of intact intestine, the most