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目的:探讨小剂量雌激素治疗绝经后泌尿系感染的临床疗效。方法:选取在我院治疗的绝经后泌尿系感染反复发作的患者120例,随机分为观察组和对照组,每组60例。对照组给予常规抗感染治疗,观察组在常规治疗基础上给予小剂量雌激素(0.4 g·次-1,每日3次)治疗,比较两组的疗效、症状消失时间、尿白细胞计数等指标。结果:治疗后,观察组的总有效率为95.00%,高于对照组的75.00%(P<0.05);观察组症状消失时间为(3.10±0.52)d,明显短于对照组的(5.04±0.73)d,差异有统计学意义(P<0.05);治疗前两组尿白细胞比较,差异无统计学意义(P>0.05),治疗后两组尿白细胞均较治疗前有所降低(P<0.05)。结论:对绝经后泌尿系感染的患者给予小剂量雌激素能有效改善患者尿路症状,值得临床推广应用。
Objective: To investigate the clinical efficacy of low-dose estrogen in treating post-menopausal urinary tract infection. Methods: 120 cases of recurrent urinary tract infection in our hospital were randomly divided into observation group and control group, 60 cases in each group. The control group was given conventional anti-infective therapy. The observation group was given low-dose estrogen (0.4 g · times-1, three times a day) on the basis of routine treatment. The curative effect, symptom disappearing time and urinary white blood cell count . Results: After treatment, the total effective rate in the observation group was 95.00%, which was significantly higher than that in the control group (75.00%, P <0.05). The symptom disappearance time in the observation group was (3.10 ± 0.52) days, which was significantly shorter than that in the control group (5.04 ± 0.73) d, the difference was statistically significant (P <0.05); before treatment, there was no significant difference in urinary leukocytes between the two groups (P> 0.05) 0.05). Conclusion: The administration of low-dose estrogen to patients with post-menopausal urinary tract infections can effectively improve the urinary tract symptoms and is worthy of clinical application.