论文部分内容阅读
氢氧化钠是药物制剂中常用的辅料,常用作pH调节剂。中国药典对其质量做了严格的控制。其中,在检查项下列出了铝盐和铁盐的检查方法,即:取本品5.0g,加稀盐酸50ml溶解后,煮沸,放冷,加氨试液使成碱性,滤过,滤渣用水洗净,并炽灼至恒重,遗留残渣不得过5mg。方法中加入盐酸可使金属盐全部溶解,溶解后,加入氨试液使金属离子形成沉淀。未经水洗的沉淀可能黏附有Na+、
Sodium hydroxide is commonly used in pharmaceutical preparations excipients, commonly used as pH regulator. Chinese Pharmacopoeia made strict control over its quality. Among them, under the inspection items listed in the aluminum and iron salt inspection methods, namely: take this product 5.0g, add diluted hydrochloric acid 50ml dissolved, boiled, let cool, add ammonia test solution to make alkaline, filtration, residue Wash with water, and burning to constant weight, leaving no residue over 5mg. The method of adding hydrochloric acid can dissolve all the metal salts, dissolved, adding ammonia test solution to form metal ions precipitation. Unwashed sediment may adhere to Na +,