潞党参与新疆党参体外均具有抗自由基作用 ,且 IC5 0 分别为 0 .111和 0 .10 1mg/ m L。动物体内实验发现潞党参对小鼠脑 SOD、MDA无明显影响 ,而新疆党参可使小鼠脑 SOD活性增强和使 MDA含量减少明显高于对照组 (P<0 .0 1) In addition, Radon Codonopsis pilosula Xinjiang had anti-free radical effects in vitro, and IC50 was 0.111 and 0.110 mg/mL, respectively. Animal experiments in vivo found that Codonopsis pilosula had no significant effect on brain SOD and MDA, while Xinjiang Codonopsis can increase SOD activity and decrease MDA content in mice significantly higher than that of the control group (P<0.01).