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目的:通过临床病例资料观察缬沙坦联合氨氯地平在Ⅱ型糖尿病合并高血压患者临床治疗中的效果。方法:选取我院收治的80例Ⅱ型糖尿病合并高血压患者作为本组研究的观察对象,按照入院先后顺序将其健康对照组与观察组各40例,对照组给予单纯氨氯地平治疗,观察组在氨氯地平的基础上联合缬沙坦,对比两组患者的治疗效果。结果:(1)观察组总有效率为95%;对照组总有效率为82.5%;观察组明显高于对照组,具有统计学意义,P<0.05。(2)治疗前,两组的空腹血糖与餐后血糖水平无明显差异;治疗后,观察组的空腹血糖与餐后血糖水平均明显低于对照组,具有统计学意义,P<0.05。结论:在Ⅱ型糖尿病合并高血压患者的临床治疗中应用缬沙坦联合氨氯地平可以明显控制血糖与血压水平,疗效确切,值得推广应用。
OBJECTIVE: To observe the effect of valsartan combined with amlodipine in the clinical treatment of type 2 diabetes mellitus patients with hypertension by clinical data. Methods: Eighty patients with type 2 diabetes mellitus and hypertension were selected as observation objects in this study. According to the sequence of hospital admission, 40 healthy controls and observation group were treated with amlodipine. The patients in control group were treated with amlodipine alone. Group of Amlodipine based on the combination of valsartan, the two groups of patients compared the therapeutic effect. Results: (1) The total effective rate in the observation group was 95%; the total effective rate in the control group was 82.5%; the observation group was significantly higher than the control group, with statistical significance (P <0.05). (2) Before treatment, there was no significant difference between fasting blood glucose and postprandial blood glucose level in both groups. After treatment, the fasting blood glucose and postprandial blood glucose level in the observation group were significantly lower than those in the control group, with statistical significance (P <0.05). Conclusion: Valsartan combined with amlodipine can obviously control the blood sugar and blood pressure in the clinical treatment of patients with type II diabetes mellitus complicated with hypertension. The curative effect is exact and worthy of popularization and application.