论文部分内容阅读
A novel derivative of glycyrrhetinic acid, (E)-ethyl 3-keto-18β-glycyrrhetinate 3- oxime C32H49NO4 (Mr = 511.72), was synthesized and structurally characterized by IR, 1H NMR and single-crystal X-ray diffraction. It belongs to monoclinic, space group P21, with a = 12.4897(12), b = 7.3190(7), c = 15.9944(14) , β = 94.833(2)o, V = 1456.9(2) 3, Z = 2, Dc = 1.167 g/cm3, μ = 0.075 mm-1, F(000) = 560, the final R = 0.0449 and wR = 0.1122. A total of 7486 reflections were collected, of which 2785 were independent (Rint = 0.0199) and 2605 were observed with I > 2σ(I). There exists an intermolecular hydrogen bond which helps to stabilize the crystal structure.
A novel derivative of glycyrrhetinic acid, (E) -ethyl 3-keto-18β-glycyrrhetinate 3-oxime C32H49NO4 (Mr = 511.72), was synthesized and structurally characterized by IR, 1H NMR and single-crystal X-ray diffraction to monoclinic space group P21 with a = 12.4897 (12) b = 7.3190 (7) c = 15.9944 (14) β β = 94.833 (2) o V = 1456.9 A total of 7486 reflections were collected, of which 2785 were independent (Rint = 0.0199) and D = 1.167 g / cm3, μ = 0.075 mm-1, F 2605 were observed with I> 2σ (I). There exists an intermolecular hydrogen bond which helps to stabilize the crystal structure.