论文部分内容阅读
用放射免疫分析法及分光光度比色法测定３０例肺心病人血内皮素１（ＥＴ１）和一氧化氮（ＮＯ）含量及两者比值（ＥＴ１／ＮＯ）。治疗前肺心病患者ＥＴ１明显高于正常人，ＮＯ则低于正常人，均Ｐ＜００１，ＥＴ１／ＮＯ比正常人高（Ｐ＜００１）；治疗后，ＥＴ１显著降低，但仍高于正常人（Ｐ＜００１），ＮＯ无明显变化（Ｐ＞００５），ＥＴ１／ＮＯ与正常人比较仍存在差异（Ｐ＜００１）。表明肺心病治疗前后均有ＥＴ１和ＮＯ失衡。提示ＥＴ１，ＮＯ含量及比值变化与肺心病病理改变有关。
Radioimmunoassay and spectrophotometry were used to determine the content of endothelin-1 (ET-1) and nitric oxide (NO) and the ratio of ET-1 / NO in 30 patients with pulmonary heart disease. Before treatment, patients with pulmonary heart disease ET 1 was significantly higher than normal, NO is lower than normal, P <001, ET 1 / NO higher than normal (P <0 01); after treatment, ET 1 was significantly lower than that in normal subjects (P <001), NO was not significantly changed (P> 005), ET 1 / NO was still significantly different from normal subjects (P <001). That before and after treatment of pulmonary heart disease ET 1 and NO imbalance. Tip ET 1, NO content and ratio changes and pathological changes of pulmonary heart disease.