目的观察红花黄色素联合纳洛酮治疗老年脑梗死的效果。方法 120例确诊老年脑梗死患者随机分为对照组和治疗组,每组60例。给予纳洛酮2 mg加入5%葡萄糖注射液250 ml中静脉滴注,1次/d,共2周;试验组在应用纳洛酮的基础上给予红花黄色素氯化钠注射液100 ml,静脉滴注1次/d,共2周。2组其他常规治疗措施无差异。治疗后观察效果并比较患者的免疫功能以及不良反应等方面的差异。结果试验组有效率为明显优于对照组(P<0.05);2组免疫功能指标在治疗后均比治疗前均有明显改善(P<0.05);试验组免疫功能指标改善明显优于对照组(P<0.05)。2组治疗过程中均无药物相关不良反应发生。结论红花黄色素联合纳洛酮对治疗是老年脑梗死效果良好,可明显改善患者的免疫功能。 Objective To observe the effect of safflor yellow combined with naloxone on senile cerebral infarction. Methods A total of 120 patients with senile cerebral infarction were randomly divided into control group and treatment group, 60 cases in each group. Given naloxone 2 mg 5% glucose injection 250 ml intravenous infusion, 1 / d, a total of 2 weeks; the experimental group on the basis of naloxone given safflower yellow sodium chloride injection 100 ml , Intravenous infusion 1 / d, a total of 2 weeks. There were no differences between the other two groups in the conventional treatment. After treatment, observe the effect and compare the patient’s immune function and adverse reactions and other differences. Results The effective rate of the experimental group was significantly better than that of the control group (P <0.05); the immune function indexes of the two groups were significantly improved after treatment (P <0.05); the immune function index of the experimental group was obviously better than that of the control group (P <0.05). There was no drug-related adverse reactions in the two groups during the course of treatment. Conclusion The combination of safflower yellow pigment and naloxone is effective in treating elderly cerebral infarction and can significantly improve the immune function of patients.