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目的探讨64层螺旋CT在评价左心室功能中的应用价值。方法对35例疑诊或确诊冠心病患者同期行心脏64层螺旋CT(64SCT)、超声心动图(Echo)及X线左室造影(LVG)检查,测量射血分数(EF)、舒张末期容积(EDV)、收缩末期容积(ESV)等三种心功能指标,三种方法检查前后不超过1周。结果 64SCT与Echo在测定左室功能方面(EDV、ESV、EF)具有高度相关性(r=0.85～0.90,P<0.01);64SCT与LVG在测定左室功能方面(EDV、ESV、EF)亦具有良好相关性(r=0.75～0.81,P<0.01)。64SCT较Echo高估了EDV、ESV(P<0.05),而EF的均值差异无显著性,一致性可被临床接受。64SCT较LVG低估了EF(P<0.05)。三种参数测量方法均有较好的可重复性。结论 64层螺旋CT与X线左室造影、超声心动图所测的EDV、ESV、EF具有较高的相关性、一致性和可重复性。64层螺旋CT是定量评价左心室功能准确、可靠的方法。
Objective To investigate the value of 64-slice spiral CT in assessing left ventricular function. Methods Sixty-five patients with suspected or confirmed coronary heart disease underwent 64-slice spiral CT (64SCT), echocardiography (Echo) and left ventricular angiography (LVG) during the same period. The ejection fraction (EF), end-diastolic volume (EDV), end-systolic volume (ESV) and other three cardiac function indicators, the three methods before and after the examination no more than 1 week. Results There was a significant correlation between 64SCT and Echo in determining left ventricular function (EDV, ESV, EF) (r = 0.85-0.90, P <0.01). The correlation between 64SCT and LVG in determining left ventricular function There was a good correlation (r = 0.75-0.81, P <0.01). Compared with Echo, 64SCT overestimated EDV and ESV (P <0.05), while there was no significant difference in mean EF between two groups. The consistency can be accepted clinically. 64SCT underestimated EF compared with LVG (P <0.05). Three kinds of parameter measurement methods are better repeatability. Conclusions The correlation between 64-slice spiral CT and X-ray left ventricle angiography and echocardiography is significant, consistent and reproducible. 64-slice spiral CT is an accurate and reliable method for quantitative assessment of left ventricular function.