肺小细胞癌以通过淋巴和血源途径引起胸腔内外广泛转移为其特征。尽管尸解胰腺转移率很高,但临床由于转移而引起的急性胰腺炎(MIAP)则少见。本文报告三例小细胞肺癌发生急性胰腺炎患者,并对其发生率、诊断、临床特点及处理进行讨论。病例报告简述如下:三例患者经纤维支气管镜活检病理证实肺小细胞癌,并有淋巴结和(或)其他脏器转移。起病以突然发生的剧烈的中上腹疼痛,伴恶心呕吐为特征;体检均有中上腹或左上腹压痛,例1、2分别于剑突下扪及10 cm及4.5 cm硬块。实验室发现,血清淀粉酶明显升高,分别为535、318、及1340Somogyi氏单位;例1、3有胰扫描及超声图检查的异常,例2仅作内窥镜逆行胰胆管造影,发现异常。按 Small cell lung cancer is characterized by extensive lymphatic and blood-borne pathways that cause extensive metastases outside the chest. Despite the high rate of autophagic pancreas metastasis, clinical acute pancreatitis (MIAP) due to metastasis is rare. This article reports three cases of small cell lung cancer in patients with acute pancreatitis, and its incidence, diagnosis, clinical features and treatment are discussed. The case reports are summarized as follows: Three patients were confirmed by bronchofibroscopy biopsy of small cell lung cancer with lymph node and / or other organ metastases. The onset was characterized by a sudden onset of severe abdominal pain accompanied by nausea and vomiting. The physical examinations included mid-upper quadrant or left-sided abdominal tenderness. Cases 1 and 2 were palpable with 10 cm and 4.5 cm lumps, respectively, under the xiphoid. The laboratory found that serum amylase was significantly increased, respectively, 535,318, and 1340Somogyi’s units; cases 1 and 3 have pancreatic scan and ultrasound abnormalities, cases 2 only for endoscopic retrograde cholangiopancreatography and found abnormal . press