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近年来,由于结核诊疗的不规范、多重耐药菌株的出现以及人类免疫缺陷病毒(HIV)等感染引起免疫力低下患者的增多,脑脊液抗酸染色及培养阳性率极低等原因,结核性脑膜炎误诊率不断增加。在临床工作中经常发现,很多结核性脑膜炎患者的临床表现,尤其是在疾病初期缺乏特异性,而辅助检查(如脑脊液和影像学)在早期也呈现非特异性,由此引起误诊漏诊,对患者的后续治疗及预后极为不利。基于此现状,本研究总结分析我院2000年3月至2012年6月收治
In recent years, due to non-standard diagnosis and treatment of tuberculosis, the emergence of multiple drug-resistant strains and human immunodeficiency virus (HIV) and other infections caused by the increase in patients with low immunity, cerebrospinal fluid acid-fast staining and culture positive rate is very low and other reasons, tuberculous meningitis Misdiagnosis rate of inflammation is increasing. In clinical practice, it is often found that the clinical manifestations of many patients with tuberculous meningitis, especially in the early stages of the disease are not specific, and the auxiliary tests (such as cerebrospinal fluid and imaging) are also nonspecific in the early stages, leading to misdiagnosis and missed diagnosis. Follow-up of patients and prognosis is extremely unfavorable. Based on this status quo, this study summarizes and analyzes our hospital from March 2000 to June 2012 admitted