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目的探讨前列腺增生(BPH)的临床特点和治疗情况。方法回顾分析近10年我科收住的1345例BPH患者的临床特点和治疗情况。结果1345例BPH患者中,表现有尿频1188例(88.3%),尿痛183例(13.6%),血尿254例(18.9%),排尿困难1213例(90.2%),有尿潴留671例(49.9%);合并肾积水89例(6.6%),膀胱结石97例(7.2%),膀胱憩室29例(2.2%)。454例(33.8%)患者尿常规提示有炎症存在;635例(47.2%)患者接受了PSA检测,结果为0.1～150μg/L,平均9.55μg/L;611例(45.4%)B超测得的前列腺体积为20～193ml,平均58.76ml;730例(54.3%)残余尿量为0～1200ml,平均99.1ml。前列腺体积随年龄增加而增大(F=2.82,P<0.01),PSA随体积增大而升高(F=8.19,P<0.01)。450例(33.5%)患者接受了前列腺开放切除,553例(41.1%)接受了TURP,TURP组患者的并发症及住院时间明显低于前者(P1=0.02,P2<0.01)。结论BPH的症状和并发症严重影响患者的生活质量,及时有效的治疗是防止并发症发生、发展的关键。TURP是治疗BPH的标准方法。
Objective To investigate the clinical characteristics and treatment of benign prostatic hyperplasia (BPH). Methods The clinical features and treatment of 1345 BPH patients admitted to our department during the past 10 years were retrospectively analyzed. Results Among the 1345 BPH patients, 1188 (88.3%) had urinary frequency, 183 (13.6%) had dysuria, 254 (18.9%) had hematuria, 1213 (90.2%) had dysuria, 671 (49.9 89 cases (6.6%) with hydronephrosis, 97 cases (7.2%) with bladder stones and 29 cases (2.2%) with bladder diverticulum. The urinalysis of 454 patients (33.8%) was suggestive of inflammation; PSA was detected in 635 patients (47.2%) with a mean of 9.55 μg / L for the range of 0.1-150 μg / L; 611 (45.4% Of the prostate volume was 20 ~ 193ml, an average of 58.76ml; 730 cases (54.3%) residual urine volume of 0 ~ 1200ml, with an average of 99.1ml. Prostate volume increased with age (F = 2.82, P <0.01), PSA increased with volume (F = 8.19, P <0.01). Open prostatectomy was performed in 450 patients (33.5%). TURP was performed in 553 patients (41.1%). Complications and hospital stay in patients with TURP were significantly lower than those in patients with TURP (P <0.02, P <0.01). Conclusion The symptoms and complications of BPH seriously affect the quality of life of patients, timely and effective treatment is to prevent the occurrence and development of complications. TURP is the standard treatment for BPH.