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目的 观察低分子质量肝素对糖尿病肾病的治疗效果。方法 6 0例糖尿病肾病患者随机分为A、B两组。A组常规治疗基础上加低分子质量肝素 (法安明 ) 5 0 0 0U每日 2次 ,皮下注射 ,10天 1个疗程。B组予以常规治疗 ,不加法安明。结果 A组治疗后尿蛋白明显减少 ,差异显著 (P <0 .0 1)。而B组治疗前后尿蛋白变化无差异 (P >0 .0 5 )。A、B两组疗效比较差异有显著性 (P <0 .0 5 )。结论 糖尿病肾病临床蛋白尿期 ,低分子质量肝素治疗对减少尿蛋白有一定疗效。
Objective To observe the therapeutic effect of low molecular weight heparin on diabetic nephropathy. Methods Sixty patients with diabetic nephropathy were randomly divided into A and B groups. A group of conventional treatment based on the addition of low molecular weight heparin (Fuming) 5 0 0 0U 2 times daily, subcutaneous injection, 10 days a course of treatment. Group B was routine treatment, without adding amion. Results After treatment, urinary protein in group A decreased significantly (P <0.01). There was no significant difference in urine protein between before and after treatment in group B (P> 0.05). There was significant difference between the two groups (P <0.05). Conclusion The clinical proteinuria of diabetic nephropathy, low molecular weight heparin therapy has a certain effect of reducing urinary protein.