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20 0 1年 2月至 2 0 0 3年 3月 ,我们采用细胞原位杂交法和吖啶橙 ( AO) /溴化乙锭 ( EB)荧光染料双重染色法检测 30例急性淋巴细胞性白血病 ( ALL )患儿化疗前后骨髓单个核细胞 Bcl- 2基因表达及细胞凋亡指数 ( AI) ,以探讨 Bcl- 2基因表达、细胞凋亡与ALL临床分型、化疗反应
From February 2001 to March 2003, we detected 30 cases of acute lymphoblastic leukemia by double staining of cell in situ hybridization and acridine orange (AO) / ethidium bromide (EB) (ALL) before and after chemotherapy in patients with bone marrow mononuclear cells Bcl-2 gene expression and apoptosis index (AI), to explore the Bcl-2 gene expression, apoptosis and ALL clinical classification, chemotherapy response