论文部分内容阅读
作者对比了伊拉地平(Isradipine)与硝苯啶治疗慢性稳定性心绞痛的疗效。 29例患者均确诊为冠状动脉疾病。研究方法为12周随机双盲对照交叉法。第1～2周为单盲安慰剂冲洗期,第3、4、5、6周为有效药物A或B滴定和治疗,第7周为单盲安慰剂冲洗期,第8、9、10、11周为有效药物A或B滴定和治疗,第12周为单盲安慰剂冲洗期。4周伊拉地平或硝苯啶的剂量为,第1周分别为2.5mg或10mg,第2周5mg或20mg,最终剂量为7.5mg或30mg,均为
The authors compared the efficacy of Isradipine and nifedipine in the treatment of chronic stable angina. All 29 patients were diagnosed with coronary artery disease. The study method was a 12-week randomized double-blind controlled crossover. Weeks 1 to 2 were single-blind placebo rinse cycles, Week 3, 4, 5 and 6 were effective A or B drug titrations and treatments, week 7 was single-blind placebo rinse cycles, Week 11 was titrated and treated with validated drug A or B and week 12 with a single blind placebo washout. The 4-week dose of ilapirtine or nifedipine was 2.5 mg or 10 mg in the first week, 5 mg or 20 mg in the second week, and the final dose was 7.5 mg or 30 mg