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目的分析急性肾损伤合并消化道出血的危险因素。方法选取512例急性肾损伤患者作为研究对象,对其消化道发生出血的危险因素进行分析,并对引起其死亡的危险因素进行分析。结果 512例急性肾损伤患者中,有53例患者合并消化道出血,42例患者为上消化道出血,11例患者为临床严重消化道出血。引起患者发生死亡的主要危险因素为中枢神经衰竭、临床严重消化道出血、血小板减少、机械通气、心功能衰竭、肝硬化。急性肾损伤合并消化道出血的患者的死亡率为52.8%,未合并消化道出血的急性肾损伤患者的死亡率为22.2%,合并消化道出血的患者的死亡率明显更高(P<0.05)。结论消化道出血是一种常见的急性肾损伤合并症,以上消化道发生出血为主。消化道发生出血的患者的死亡率明显增高,急性肾损伤患者的死亡率与消化道出血存在着密切的关系。
Objective To analyze the risk factors of acute renal injury combined with gastrointestinal bleeding. Methods A total of 512 patients with acute renal injury were selected as study subjects, and their risk factors for gastrointestinal bleeding were analyzed and the risk factors causing their death were analyzed. Results Of 512 patients with acute renal injury, 53 patients had gastrointestinal bleeding, 42 patients had upper gastrointestinal bleeding, and 11 patients had clinically severe gastrointestinal bleeding. The main risk factors for death in patients were central nervous system failure, clinically severe gastrointestinal bleeding, thrombocytopenia, mechanical ventilation, heart failure, and cirrhosis. The mortality rate was 52.8% in acute kidney injury patients with gastrointestinal bleeding, 22.2% in patients with acute renal injury without gastrointestinal bleeding, and significantly higher in patients with gastrointestinal bleeding (P <0.05) . Conclusions Gastrointestinal hemorrhage is a common complication of acute renal injury. Hemorrhage mainly occurs in the upper gastrointestinal tract. Mortality in patients with gastrointestinal bleeding was significantly higher mortality in patients with acute kidney injury and gastrointestinal bleeding are closely related.