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目的:探讨多药联合治疗妊娠期肝内胆汁瘀积症的临床效果。方法:我院自2010年2月至2012年2月收治妊娠期肝内胆汁瘀积症患者30例,随机分为治疗组和对照组,每组各15例,治疗组应用多药联合治疗,对照组应用熊去氧胆酸治疗。观察两组患者实际临床症状改善情况,统计两组患者的实际治疗效果。结果:治疗组15例患者中,显效9例,有效6例,无效0例,总有效率为100.00%;对照组15例患者中,显效3例,有效7例,无效5例,总有效率为66.67%。结论:多药联合治疗妊娠期肝内胆汁瘀积症疗效显著,值得临床推广应用。
Objective: To investigate the clinical effect of multi-drug combined treatment of intrahepatic cholestasis of pregnancy. Methods: From February 2010 to February 2012, 30 patients with intrahepatic cholestasis of pregnancy were treated in our hospital. They were randomly divided into treatment group and control group with 15 cases in each group. The treatment group received multi-drug combination therapy, The control group was treated with ursodeoxycholic acid. The actual clinical symptoms in both groups were observed and the actual treatment effect was calculated. Results: Of the 15 patients in the treatment group, 9 were markedly effective, 6 were effective, 0 were ineffective, and the total effective rate was 100.00%. Among 15 patients in the control group, 3 were markedly effective, 7 effective and 5 ineffective. The total effective rate 66.67%. Conclusion: Multi-drug combination treatment of intrahepatic cholestasis of pregnancy significant effect, worthy of clinical application.