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回春膏能增强麻醉狗阴道平滑肌张力和持续时间。提取液对大鼠阴道离体平滑肌的作用与狗相似。回春膏和提取液给小鼠灌胃,最大耐受量分别为8和80g/kg。提取液给小鼠腹腔注射:LD_(50)3.6±0.58g/kg;回春膏大鼠灌胃28天无毒性,水悬液给大鼠、狗灌胃对肝肾有轻度毒性。回春膏对大鼠生殖无毒性。回春膏及提取液局部刺激性极小,几无过敏反应。
Rejuvenation cream can increase vaginal smooth muscle tone and duration in anesthetized dogs. The effect of the extract on rat vaginal smooth muscle was similar to that of dogs. Rejuvenation cream and extracts were given to the mice and the maximum tolerated doses were 8 and 80 g/kg, respectively. The mice were intraperitoneally injected with the extract: LD_(50) 3.6±0.58g/kg; the rejuvenating ointment rats were intragastric for 28 days without toxicity, and the water suspension was given to the rats and the dogs were intragastrically administered with mild toxicity to the liver and kidney. Rejuvenation cream is non-toxic to rat reproduction. The rejuvenation cream and extract have minimal local irritation and few allergic reactions.