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目的:探讨适宜基层地区细胞学诊断为ASCUS病例有效的处理方法。方法:将诊断为ASCUS的896例病例分为两组,第一组543例重复细胞学检查,结果≥ASCUS病例进行宫颈活检术+组织病理学检查;第二组353例直接宫颈活检术+组织病理学检查。另外对组织病理学检查结果与各年龄段的关系进行分析。结果:第一组重复细胞学检查无上皮内病变55例、ASCUS 158例、ASC-H 39例、LSIL 255例、HSIL36例;其中488例≥ASCUS病例组织病理学检查结果炎症179例、CINⅠ200例、CINⅡ49例、CINⅢ59例、宫颈癌1例。第二组直接组织病理学检查结果炎症137例、CINⅠ134例、CINⅡ47例、CINⅢ34例、宫颈癌1例,两组组织病理学检查差异无统计学意义。≥CINⅡ的检出率与各年龄段间差异有统计学意义,40～44岁年龄段CINⅡ及以上检出率明显高于其他各年龄段,其次是35～39岁年龄段和45～49岁年龄段。结论:在基层地区细胞学诊断为ASCUS的病例可根据当地的实际情况任选一种处理方案,重点对35～49岁年龄段的病例加强临床监测。
Objective: To explore the appropriate treatment of ASCUS cases suitable for primary diagnosis of cytology. Methods: 896 cases diagnosed as ASCUS were divided into two groups, the first group of 543 cases of repeat cytology, the results ≥ ASCUS cases of cervical biopsy + histopathological examination; the second group of 353 cases of direct cervical biopsy + tissue Pathological examination. In addition, the relationship between histopathological findings and various age groups was analyzed. Results: The first group of repeat cytology without epithelial lesions in 55 cases, ASCUS 158 cases, ASC-H 39 cases, LSIL 255 cases, HSIL36 cases; of which 488 cases ≥ASCUS case histopathological findings of inflammation in 179 cases, CIN Ⅰ 200 cases , CINⅡ49 cases, CINⅢ59 cases, cervical cancer in 1 case. The second group of 137 cases of direct histopathological inflammatory findings, CINI134 cases, CINII47cases, CINIII34cases of cervical cancer in 1 case, histopathological examination showed no significant difference between the two groups. The detection rate of CINⅡwas significantly different from that of other age groups. The detection rates of CINⅡand above in 40-44 years old group were significantly higher than those in other age groups, followed by 35-39 years old group and 45-49 years old group generation. CONCLUSIONS: In the primary area, cytological diagnosis of ASCUS cases may be based on the local situation of an optional treatment options, focusing on 35 to 49 years of age cases to strengthen clinical monitoring.